Cognac polyphenolic compounds increase bradykinin-induced nitric oxide production in endothelial cells

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Cognac polyphenolic compounds increase bradykinin-induced nitric oxide production in endothelial cells.

We recently reported that in vitro Cognac polyphenolic compounds (CPC) induce NO-dependent vasorelaxant effects and stimulate cardiac function. In the present study, we aim to investigate the effect of CPC on both nitric oxide (NO) and superoxide anions (O(2)(-)) production in cultured human endothelial cells. In addition, its effect on the bradykinin (BK)-induced NO production was also tested....

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ژورنال

عنوان ژورنال: Physiological Research

سال: 2008

ISSN: 1802-9973,0862-8408

DOI: 10.33549/physiolres.931366